Mesothelioma is an incurable asbestos cancer. This short film was produced to raise awareness of the issues around mesothelioma. It includes interviews with people who have the disease. It was produced for Action Mesothelioma day on belhalf of Forum of Asbestos Victim Support Groups. For more information visit www.ActionMeso.info

Peritoneal mesothelioma is less common than pleural mesothelioma, but both of these typically malignant mesotheliomas can be just as tragic. Peritoneal mesothelioma begins in the abdominal cavity, as opposed to the lungs and pleural areas of pleural mesothelioma. “Peritoneal” means it has to do with the peritoneum, which is a membrane that surrounds the abdominal area. “Pleural” refers to the pleura which is a membrane that surrounds the lungs. There is also a “pericardial” mesothelioma which targets the heart membrane first.

The lungs, abdominal area and heart all have a membrane made up of mesothelial cells, named the mesothelium. A cancerous attack of these membrane areas are mesotheliomas. Asbestos is the cause of peritoneal mesothelioma, pleural mesothelioma and pericardial mesothelioma in well over 90% of the cases. There are a few rare recorded cases of malignant mesothelioma when asbestos exposure was not identified. If you have been exposed to asbestos, there is a high chance you will suffer from an asbestos-caused disease such as asbestosis or pleural plaques. However, not all asbestos-caused diseases are fatal.

Peritoneal mesothelioma, pleural mesothelioma and pericardial mesothelioma can be fatal malignant mesotheliomas which spread uncontrollably, or they can be benign, when the tumor stays where it is and can likely be removed. Unexplainable weight loss is a mesothelioma symptom which may occur in as many as 90% of benign and malignant mesothelioma. Generally, benign mesothelioma tends to show less symptoms than malignant mesothelioma. Mesothelioma symptoms for peritoneal mesothelioma almost always includes abdominal pain. This is because there is excess fluid between the peritoneal membrane and the abdomen walls. Pleural mesothelioma has excess fluid in the pleural area and this causes shortness of breath and chest pain.

The mesothelioma symptoms of pleural mesothelioma and pericardial mesothelioma are not as outwardly visible as the symptoms of peritoneal mesothelioma. In peritoneal mesothelioma, the abdomen can appear larger. Tumor masses may be visible, but external tumor visibility only occurs in a minority of peritoneal mesothelioma cases. Nausea is a common mesothelioma symptom with peritoneal mesothelioma, and the abdominal area will also be very tender.

In a healthy peritoneal area between the membrane and the wall, the peritoneal fluid helps the intestines move food. In peritoneal mesothelioma however, excess fluid causes bowel obstruction. The mesothelioma symptoms of extra fluid and bowel obstruction both contribute to abdominal pain. The bowel obstruction can also produce mesothelioma symptoms of constipation and diarrhea. Many peritoneal malignant mesothelioma patients have reported mesothelioma symptoms of a burning sensation in the abdomen. Mesothelioma symptoms for peritoneal malignant mesothelioma may not surface for 20-30 years after asbestos exposure, but it generally surfaces sooner than pleural mesothelioma.

Peritoneal mesothelioma is fortunately rare, however its rarity sometimes makes it harder to diagnose. The symptoms are similar to hernias and gall bladder problems, and identifying peritoneal mesothelioma in a CT scan is difficult. The medical industry is aware that asbestos-related diseases will be escalating over the upcoming years, and treatment for peritoneal malignant mesothelioma is undergoing many clinical trials. If you have been exposed to asbestos and have unexplainable abdominal pain and are experiencing unexplained weight loss, begin preliminary testing for peritoneal mesothelioma. The sooner the testing begins, the higher the chances for symptomatic relief, and hopefully today’s mesothelioma clinical trials will lead to a mesothelioma cure in the future.

Mesothelioma Video: In this video a medical doctor explains types of mesothelioma. In the full DVD www.mesodvd.com, he explains mesothelioma stages, mesothelioma types, mesothelioma symptoms, and mesothelioma diagnosis. Most importantly mesothelioma treatments are discussed. This is the…

MESOSELIOMA MESOMARK BLOOD TEST
The Food and Drug Administration (FDA) approved the MESOMARK assay to help monitor response to treatment in malignant mesothelioma patients. The MESOMARK test signifies the beginning of a new era in monitoring mesothelioma malignancies,” said Dr. W. Jeffrey Allard, vice president and chief scientific officer of Fujirebio Diagnostics. “As the first in-vitro test for patients with this aggressive disease, it will enable doctors to more accurately detect recurrence and monitor treatment of patients.”
The MESOMARK Assay test kit was developed to measure levels of a biomarker, mesothelin, in serum. Biomarkers are substances found in higher-than-normal concentrations in the blood, urine or body tissues of patients with certain types of cancers. The test may be used to monitor patients confirmed as having mesothelioma, for recurrence in patients following surgery, or for measuring response to therapies.
“Current diagnostic tests are less than ideal for quantification of changes in tumor volume, which is key to managing the disease,” continued Allard. “As the MESOMARK results correlate with tumor volume*, it provides a much needed tool for monitoring patient status. It is our plan to collect additional data in the future to support the use of the test to detect mesothelioma.”

MESOMARK test are now making it possible – with a simple blood test -to monitor response to treatment and to detect recurrence following treatment. This provides an important head start to patients racing against this aggressive cancer. “The Meso Foundation is the national research funding, patient support and advocacy organization dedicated to eradicating mesothelioma as a life-threatening disease.
Those wishing to take part in MESOMARK testing will be asked to provide one or more samples of blood. The blood samples will then be sent to a national reference laboratory for testing. In conjunction with other clinical and laboratory data obtained by your doctor, decisions regarding your treatment and care may be simplified. You may discontinue testing at any time.

LINKS:
Diagnisis Mesothelioma